Richard W J Groen Selected Research

ADP-ribosyl Cyclase 1

1/2019	Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor-engineered T Cells.
1/2017	A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization.

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Richard W J Groen Research Topics

Disease

24	Multiple Myeloma 12/2021 - 01/2010
17	Neoplasms (Cancer) 12/2021 - 09/2008
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2021 - 02/2014
3	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 11/2010
2	Carcinogenesis 10/2019 - 01/2006
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2017 - 01/2016
2	Lymphoma (Lymphomas) 01/2015 - 09/2008
2	Bone Diseases (Bone Disease) 03/2014 - 11/2011
1	Acute Biphenotypic Leukemia (Leukemia, Mixed Cell) 01/2017
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 02/2014
1	Graft vs Host Disease (Graft-Versus-Host Disease) 03/2013
1	Leukemia 09/2008
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2006

Drug/Important Bio-Agent (IBA)

7	daratumumabIBA 05/2021 - 01/2015
5	Chimeric Antigen ReceptorsIBA 12/2021 - 01/2016
4	Bortezomib (Velcade)FDA Link 10/2020 - 10/2013
4	Pharmaceutical PreparationsIBA 01/2019 - 02/2014
3	AntigensIBA 12/2021 - 01/2017
3	CytokinesIBA 01/2017 - 01/2016
2	SurvivinIBA 01/2020 - 10/2013
2	Proteins (Proteins, Gene)FDA Link 10/2019 - 01/2016
2	ADP-ribosyl Cyclase 1IBA 01/2019 - 01/2017
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2019 - 12/2017
2	AntibodiesIBA 01/2018 - 01/2015
2	Lenalidomide (CC 5013)FDA Link 12/2017 - 06/2015
2	Antigen Receptors (Antigen Receptor)IBA 01/2017 - 01/2016
2	Monoclonal AntibodiesIBA 01/2016 - 06/2015
2	LuciferasesIBA 10/2013 - 07/2012
1	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 12/2021
1	Oncogene Proteins (Oncogene Protein)IBA 01/2021
1	MicellesIBA 12/2020
1	carfilzomibIBA 12/2020
1	7- ethyl- 7- hydroxy- 10H- 1,3- Dioxolo(4,5- g)pyrano(3',4':6,7)indolizino(1,2- b)quinoline- 8,11(7H,12H)- dioneIBA 01/2020
1	InterferonsIBA 10/2019
1	Polycomb Repressive Complex 2IBA 10/2019
1	RNA (Ribonucleic Acid)IBA 10/2019
1	Histones (Histone)IBA 10/2019
1	Lysine (L-Lysine)FDA Link 10/2019
1	GlucocorticoidsIBA 01/2019
1	Liposomes (Liposome)IBA 01/2019
1	EpitopesIBA 01/2019
1	Single-Chain AntibodiesIBA 01/2019
1	dexamethasone 21-phosphate FDA LinkGeneric 01/2019
1	Complement System Proteins (Complement)IBA 12/2017
1	Surface Antigens (Surface Antigen)IBA 01/2017
1	sepantroniumIBA 01/2016
1	Immunoglobulin G (IgG)IBA 01/2015
1	Citric Acid (Citrate)FDA LinkGeneric 03/2014
1	Proteasome InhibitorsIBA 03/2014
1	MLN2238IBA 03/2014
1	ixazomibIBA 03/2014
1	PhenothiazinesIBA 02/2014
1	Perphenazine (Trilafon)FDA LinkGeneric 02/2014
1	Antipsychotic Agents (Antipsychotics)IBA 02/2014
1	Caspase 3 (Caspase-3)IBA 10/2013
1	CateninsIBA 01/2012
1	Cadherins (E-Cadherin)IBA 11/2011
1	Minor Histocompatibility AntigensIBA 11/2010
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2010
1	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 11/2010
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2010
1	Syndecan-1 (Syndecan 1)IBA 01/2010
1	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/2010
1	TCF Transcription FactorsIBA 09/2008
1	beta CateninIBA 09/2008
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2006
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2006
1	HGF activatorIBA 01/2006

Therapy/Procedure

7	Therapeutics 01/2021 - 11/2010
4	Immunotherapy 01/2021 - 11/2010
1	Intravenous Injections 12/2020
1	Transplantation 01/2017
1	Drug Therapy (Chemotherapy) 06/2015
1	Stem Cell Transplantation 03/2013
1	Injections 11/2010